min read
June 20, 2024

Leaky Gut Syndrome: What You Should Know

Have you ever heard of "leaky gut syndrome"? No, it's not the latest craze in leaky plumbing technology, although it does involve a certain level of leakage - just not where you want it. Leaky gut syndrome is a condition that occurs when the lining of your intestines becomes damaged, allowing harmful toxins and bacteria to seep into your bloodstream and wreak havoc on your body.

Now, I know what you're thinking - "Gross, why would I want to learn more about this?" But hold on just a second! As unpleasant as leaky gut may sound, it could be the root cause of some of your most persistent health problems. Symptoms like bloating, fatigue, joint pain, and even skin issues can all be linked to this condition.

In this article, we're going to dive into the world of leaky gut syndrome and explore why testing for it could be the missing piece to solving your health puzzle. So sit back, grab a cup of tea (or whatever your beverage of choice may be), and let's get to the bottom of this leaky business!

How do you know if you have a leaky gut?

To some extent, all of us experience a certain degree of permeability in our gut lining. This is because the tight junctions that seal the intestinal walls loosen temporarily every time we eat, allowing nutrients and fluids to enter our bloodstream. Tight junctions are special proteins that connect the cells in your gut lining. These are similar to shoelaces. When the gaps between the cells are tight, they close, but when they are loose, they widen to allow molecules to pass through. 

In some cases, gut microbes and their by-products can also pass through at the same time. However, prolonged loosening of these tight junctions can lead to a continuous influx of microbes, endotoxins, and undigested food particles, which can trigger an immune response and cause chronic inflammation. Such inflammation may lead to a multitude of health issues that can affect various parts of the body. These include:

  • Autoimmune disorders and reactions
  • Inflammatory bowel disease, such as Irritable Bowel Syndrome (IBS)
  • Learning disabilities, particularly autism
  • Food sensitivities and allergies
  • Asthma
  • Skin ailments such as eczema and psoriasis
  • Joint pain, arthritis and other body aches
  • Increased risk of developing diabetes
  • Fatigue
  • Changes in mood, appetite and body weight

Testing for a Leaky Gut

Functional medicine practitioners use a variety of tests to determine if someone has a leaky gut. Here are some of the most common methods:

Intestinal Permeability Assessment: This test involves drinking a solution containing sugar molecules of different sizes. After a certain amount of time, a urine sample is collected and analyzed to see how much of the different sugars have been absorbed.

Lactulose/Mannitol Test: This test is similar to the intestinal permeability assessment but uses two different types of sugar molecules. Lactulose is a larger molecule that should not normally be absorbed, while mannitol is a smaller molecule that should be easily absorbed. After consuming a solution containing both sugars, a urine sample is collected and analyzed to see how much of each has been absorbed.

Stool Test: A comprehensive stool test can help identify imbalances in gut bacteria and other markers of gut health, including inflammation, digestive function, and immune function.

Blood Test: Blood tests can help identify antibodies to specific foods or bacteria that may be contributing to leaky gut and inflammation.

It is important to note that none of these tests are 100% conclusive on their own and should be used in combination with a thorough clinical evaluation by a functional medicine practitioner. Treatment for leaky gut typically involves dietary and lifestyle changes, targeted supplementation, and other therapies to restore gut health and reduce inflammation.